Intravenous Immunoglobulin in Acute Rheumatic Fever
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چکیده
منابع مشابه
Intravenous Immunoglobulin in Acute Rheumatic Fever
Background—Acute rheumatic fever (ARF) remains the leading cause of acquired heart disease in children worldwide. No therapeutic agent has been shown to alter the clinical outcome of the acute illness. Immunological mechanisms appear to be involved in the pathogenesis of ARF. Intravenous immunoglobulin (IVIG), a proven immunomodulator, may benefit cardiac conditions of an autoimmune nature. We ...
متن کاملIntravenous immunoglobulin in acute rheumatic fever: a randomized controlled trial.
BACKGROUND Acute rheumatic fever (ARF) remains the leading cause of acquired heart disease in children worldwide. No therapeutic agent has been shown to alter the clinical outcome of the acute illness. Immunological mechanisms appear to be involved in the pathogenesis of ARF. Intravenous immunoglobulin (IVIG), a proven immunomodulator, may benefit cardiac conditions of an autoimmune nature. We ...
متن کاملImmunologic Factors in Acute Rheumatic Fever Compared to Rheumatic Heart Disease
Background/Objective: To clarify the state of different immunologic factors in patients with acute rheumatic fever (ARF) and rheumatic heart disease (RHD) compared to healthy individuals.Patients and Methods: Patients with ARF (#21), patients with RHD six months after the onset of ARF (#19), and healthy children from the same age group with normal physical examination and no history of pharyngi...
متن کاملAcute rheumatic fever.
Acute rheumatic fever is an inflammatory response to group A streptococcal infectionwhich typically occurs two to three weeks after a throat infection.Worldwide, approximately 500 000 new cases of acute rheumatic fever occur annually, and at least 15 million people have chronic rheumatic heart disease. 2 Acute rheumatic fever is characterised by a clinical syndrome, and the most common manifest...
متن کاملAcute Rheumatic Fever and Rheumatic Carditisin Izmir
Acute rheumatic fever is a non-suppurative complication of Streptococcus pyogenes which only licks the joints, however bites the heart valves, particularly the mitral, aortic or both, rarely the tricuspid valve, resulting in valvular endothelial ulceration, collagen degeneration, neovascularization, interstitial calcification and fibrosis associated with lymphocytic infiltration [1]. Currently ...
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ژورنال
عنوان ژورنال: Circulation
سال: 2001
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.103.3.401